The Semantic Web (SW) deployment is now a realization and the amount of semantic annotations is ever increasing thanks to several initiatives that promote a change in the current Web towards the Web of Data, where the semantics of data become explicit through data representation formats and standards such as RDF/(S) and OWL. However, such initiatives have not yet been accompanied by e cient intelligent applications that can exploit the implicit semantics and thus, provide more insightful analysis. In this paper, we provide the means for e ciently analyzing and exploring large amounts of semantic data by combining the inference power from the annotation semantics with the analysis capabilities provided by OLAP-style aggregations, navigation, and reporting. We formally present how semantic data should be organized in a well-de ned conceptual MD schema, so that sophisticated queries can be expressed and evaluated. Our proposal has been evaluated over a real biomedical scenario, which demonstrates the scalability and applicability of the proposed approach.