Peripheral but critical: Translation of germ granule mRNAs in zebrafish

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2023 English Publisher:Elsevier BVJournal:Developmental Cell, volume 58, pages 1,517-1,518 (issn: 1534-5807,

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Authors: Tatjana Trcek;

doi: 10.1016/j.devcel.2023.08.008

pmid: 37699335

Peripheral but critical: Translation of germ granule mRNAs in zebrafish

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Abstract

RNA granule components occupy distinct positions within granules. However, the significance behind this organization is unclear. In this issue of Developmental Cell, Westerich et al. show that the periphery of the zebrafish germ granules promotes mRNA translation while its interior represses it, which is critical for germ cell establishment.

Related Organizations

Johns Hopkins University
United States

Keywords

Germ Cells, Animals, RNA, Messenger, Germ Cell Ribonucleoprotein Granules, Zebrafish

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