Autophagy Suppresses Breast Cancer Metastasis

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2020 English Publisher:Elsevier BVJournal:Developmental Cell, volume 52, pages 542-544 (issn: 1534-5807,

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Authors: Benjamin N, Ostendorf; Sohail F, Tavazoie;

doi: 10.1016/j.devcel.2020.02.005

pmid: 32155434

Autophagy Suppresses Breast Cancer Metastasis

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Abstract

Cancer cells need to acquire specific molecular traits in order to spread to distant organs. In this issue of Developmental Cell, Marsh et al. show that autophagy restricts the outgrowth of breast cancer metastases in contrast to its impact on primary tumor progression.

Related Organizations

Rockefeller University
United States

Keywords

Autophagy, Disease Progression, Intracellular Signaling Peptides and Proteins, Animals, Humans, Proteins, Breast Neoplasms, Mammary Neoplasms, Animal

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