
pmid: 31550460
In this issue of Developmental Cell, Ren et al. (2019) identify the embryonic origin of cardiac pacemaker cells in zebrafish and implicate Wnt5b in promoting their differentiation. Furthermore, canonical Wnt activation in human stem cell-derived cardiac progenitors produces functional pacemaker cells in vitro, advancing the therapeutic potential of biological pacemakers.
Mesoderm, Wnt Proteins, Animals, Humans, Cell Differentiation, Myocytes, Cardiac, Wnt Signaling Pathway
Mesoderm, Wnt Proteins, Animals, Humans, Cell Differentiation, Myocytes, Cardiac, Wnt Signaling Pathway
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