The Hippo Signaling Pathway in Development and Disease
Copyright policy )The Hippo Signaling Pathway in Development and Disease
The Hippo signaling pathway regulates diverse physiological processes, and its dysfunction has been implicated in an increasing number of human diseases, including cancer. Here, we provide an updated review of the Hippo pathway; discuss its roles in development, homeostasis, regeneration, and diseases; and highlight outstanding questions for future investigation and opportunities for Hippo-targeted therapies.
- The University of Texas Southwestern Medical Center United States
- Howard Hughes Medical Institute United States
Exosome Multienzyme Ribonuclease Complex, Neoplasms, Animals, Gene Expression Regulation, Developmental, Humans, Cell Cycle Proteins, Signal Transduction, Transcription Factors
Exosome Multienzyme Ribonuclease Complex, Neoplasms, Animals, Gene Expression Regulation, Developmental, Humans, Cell Cycle Proteins, Signal Transduction, Transcription Factors
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