
pmid: 31211988
In this issue of Developmental Cell, Cho et al. (2019) find that lamin-A levels in the nuclear envelope are regulated in response to mechanical stimuli to prevent the nucleus from rupture, keep DNA repair factors in the nucleus, and consequentially "mechano-protect the genome."
Cell Nucleus, Nuclear Envelope, Cell Cycle Checkpoints, Lamin Type A, DNA Damage
Cell Nucleus, Nuclear Envelope, Cell Cycle Checkpoints, Lamin Type A, DNA Damage
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