
pmid: 29486188
There is mounting circumstantial evidence that ploidy, a cell's relative DNA content, is in part responsible for the differential cardiac regenerative capacity observed between regenerative and non-regenerative organisms. In this issue of Developmental Cell, González-Rosa et al. (2018) provide direct evidence that polyploid cardiomyocytes have reduced proliferative and regenerative potential.
Ploidies, Regeneration, Heart, Myocytes, Cardiac
Ploidies, Regeneration, Heart, Myocytes, Cardiac
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