TrkA Bumps into Its Future Self

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2017 English Publisher:Elsevier BVJournal:Developmental Cell, volume 42, pages 557-558 (issn: 1534-5807,

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Authors: Kelly, Barford; Austin, Keeler; Christopher, Deppmann; Bettina, Winckler;

doi: 10.1016/j.devcel.2017.09.002

pmid: 28950095

TrkA Bumps into Its Future Self

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Abstract

In neurons, correct targeting of receptors to the axon is critical for cell survival and circuit formation. In this issue of Developmental Cell, Yamashita et al. (2017) report that the ER-resident phosphatase PTP1B is required to prime TrkA for axonal transport.

Related Organizations

University of Virginia
United States

Keywords

Neurons, Cell Survival, Humans, Receptor, trkA, Axonal Transport, Axons

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