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Developmental Cell
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Developmental Cell
Article . 2016 . Peer-reviewed
License: Elsevier Non-Commercial
Data sources: Crossref
https://pubmed.ncbi.nlm.nih.go...
Article . 2017
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https://dx.doi.org/10.1016/j.d...
Article
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Institutional Repository for Molecular Medicine (MDC)
Other literature type . 2016
Data sources: Institutional Repository for Molecular Medicine (MDC)
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Examining Topological Domain Influence on Enhancer Function

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Dec 2016 English Publisher:Elsevier BVJournal:Developmental Cell, volume 39, pages 523-524 (issn: 1534-5807, Copyright policy )
Authors: Beagrie, R.A.; Pombo, A.;

doi: 10.1016/j.devcel.2016.11.011

pmid: 27923117

Examining Topological Domain Influence on Enhancer Function

Abstract

Enhancers regulate the expression of target genes across large genomic distances, but it is unclear how recently discovered topological domains affect this regulation. Reporting in this issue of Developmental Cell, Symmons et al. (2016) show that the endogenous Shh topological domain promotes functional interactions between Shh and its remote enhancer.

Related Organizations
Keywords

Enhancer Elements, Genetic, Cardiovascular and Metabolic Diseases, Gene Expression Regulation, Developmental

  • BIP!
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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
Green
hybrid