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A Pluripotency Platform for Prdm14

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jul 2016 France, Germany English Publisher:Elsevier BVJournal:Developmental Cell, volume 38, pages 3-5 (issn: 1534-5807, Copyright policy )
Authors: Burton, Adam; Torres-Padilla, Maria-Elena;

doi: 10.1016/j.devcel.2016.06.030

pmid: 27404351

A Pluripotency Platform for Prdm14

Abstract

The tripartite network of Prdm14, Blimp1, and AP2γ is essential for the important process of germ cell specification, but their precise molecular mechanisms of action remain lacking. Tu and colleagues (2016) report in Nature that the transcriptional co-repressor CBFA2T2 is an essential interactor protein regulating PRDM14 function, shedding light into the mechanisms directing germline formation and pluripotency.

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France, Germany
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Keywords

DNA-Binding Proteins, Pluripotent Stem Cells, Repressor Proteins, Germ Cells, Transcription Factor AP-2, Gene Expression Regulation, Developmental, Humans, RNA-Binding Proteins, Positive Regulatory Domain I-Binding Factor 1, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Transcription Factors

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 2
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
hybrid