How Toll Met Hippo

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2016 English Publisher:Elsevier BVJournal:Developmental Cell, volume 36, pages 246-248 (issn: 1534-5807,

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Authors: Nie, Yingchao; Ip, Y. Tony;

doi: 10.1016/j.devcel.2016.01.019

pmid: 26859349

How Toll Met Hippo

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Abstract

Toll and Hippo are two seemingly disparate pathways that regulate innate immunity and tissue growth, respectively. Reporting recently in Cell, Liu et al. (2016) tie them together by demonstrating that microbial infection activates Toll, which then signals to both pathways to modulate the antimicrobial response.

Related Organizations

University of Massachusetts Medical School
United States

Keywords

Male, Drosophila melanogaster, Animals, Immunity, Innate, Developmental Biology, Signal Transduction

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