
pmid: 26418291
How the cell builds a spindle remains an open question. In this issue of Developmental Cell, Shimamoto, Forth, and Kapoor (2015) show that kinesin-5 motor ensembles can exert sliding forces that scale with microtubule overlap length. This behavior could allow microtubule architecture-dependent modulation of force and contribute to spindle self-organization.
Xenopus laevis, Cross-Linking Reagents, Biochemistry and cell biology, Behavioral and Social Science, Animals, Kinesins, Biochemistry and Cell Biology, Spindle Apparatus, Biological Sciences, Xenopus Proteins, Medical and Health Sciences, Microtubules, Developmental Biology
Xenopus laevis, Cross-Linking Reagents, Biochemistry and cell biology, Behavioral and Social Science, Animals, Kinesins, Biochemistry and Cell Biology, Spindle Apparatus, Biological Sciences, Xenopus Proteins, Medical and Health Sciences, Microtubules, Developmental Biology
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