With NuRD, HDACs Go “Nerdy”
Copyright policy ) Sun, Yi Eve; Cheng, Liming; Hu, Keping;
With NuRD, HDACs Go “Nerdy”
Reporting in a recent issue of Neuron, Yamada et al. (2014) show that the histone deacetylase (HDAC)-containing NuRD complex plays a critical role in shutting down expression of specific synaptogenesis-related genes in the cerebellum, resulting in enhanced differentiation of presynaptic structures. This work suggests that HDACs in neurons acquire specificity through NuRD.
- Tongji University China (People's Republic of)
- Chinese Academy of Medical Sciences & Peking Union Medical College China (People's Republic of)
- Tongji Hospital China (People's Republic of)
- PEKING UNION MEDICAL COLLEGE China (People's Republic of)
- University of California, Los Angeles United States
Brain Chemistry, Synapses, Animals, Humans, Promoter Regions, Genetic, Developmental Biology, Mi-2 Nucleosome Remodeling and Deacetylase Complex
Brain Chemistry, Synapses, Animals, Humans, Promoter Regions, Genetic, Developmental Biology, Mi-2 Nucleosome Remodeling and Deacetylase Complex
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 5
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