Caspase-3, Shears for Synapse Pruning
Copyright policy )Caspase-3, Shears for Synapse Pruning
Motor neurons regulate neuromuscular junction formation by using agrin to stimulate acetylcholine receptor clustering and using acetylcholine to disperse unnecessary receptor clusters on muscle fibers. Wang et al. (2014) now report in this issue of Developmental Cell a critical role for caspase-3 in intracellular mechanisms of acetylcholine-induced dispersal.
- Augusta University United States
- Georgia Regents University United States
- Charlie Norwood VA Medical Center United States
Caspase 3, Dishevelled Proteins, Neuromuscular Junction, Animals, Synaptic Potentials, Muscle, Skeletal, Phosphoproteins, Synaptic Transmission, Developmental Biology, Adaptor Proteins, Signal Transducing
Caspase 3, Dishevelled Proteins, Neuromuscular Junction, Animals, Synaptic Potentials, Muscle, Skeletal, Phosphoproteins, Synaptic Transmission, Developmental Biology, Adaptor Proteins, Signal Transducing
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