Squeezing into Differentiation

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2011 English Publisher:Elsevier BVJournal:Developmental Cell, volume 21, pages 607-608 (issn: 1534-5807,

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Authors: Ladher, Raj K.;

doi: 10.1016/j.devcel.2011.09.017

pmid: 22014519

Squeezing into Differentiation

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Abstract

The earliest steps in tooth development depend on signaling interactions that result in the condensation of mandibular mesenchyme into the tooth bud. Reporting in this issue of Developmental Cell, Mammoto et al. (2011) find that chemotactic signals coordinate condensation and that the compressive force generated is sufficient to induce tooth bud gene expression.

Related Organizations

RIKEN
Japan
RIKEN Center for Biosystems Dynamics Research
Japan

Keywords

Developmental Biology

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