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Tuning In to Noise: Epigenetics and Intangible Variation

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2010 Australia English Publisher:Elsevier BVJournal:Developmental Cell, volume 19, pages 649-650 (issn: 1534-5807, Copyright policy )
Authors: Whitelaw, Nadia C.; Chong, Suyinn; Whitelaw, Emma;

doi: 10.1016/j.devcel.2010.11.001

pmid: 21074715

Tuning In to Noise: Epigenetics and Intangible Variation

Abstract

In this special issue of Developmental Cell, we discuss the role of chromatin in phenotypic variation as a counterpoint to the reviews on chromatin dynamics in development and cancer. We highlight some recent work on the role of chromatin in transcriptional noise in yeast and Caenorhabditis elegans and consider the implications in understanding intangible variation or developmental noise in mammals.

Country
Australia
Related Organizations
Keywords

Stochasticity, 1300 Biochemistry, Transcription, Genetic, Genetic Variation, Genetics and Molecular Biology, Chromatin, Epigenesis, Genetic, 1309 Developmental Biology, 1307 Cell Biology, 1300 Biochemistry, Genetics and Molecular Biology, Yeasts, 1312 Molecular Biology, Animals, Gene-expression, Variability, Caenorhabditis elegans, Developmental Biology

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 18
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
18
Top 10%
Top 10%
Top 10%
hybrid
Related to Research communities
Cancer Research