The EmERgence of Autophagosomes
Copyright policy )The EmERgence of Autophagosomes
Autophagosomes are large double-membrane vesicles that enclose cytoplasmic components targeting them for degradation. Two recent reports reveal that phagophores, the autophagosome precursors, are surrounded by and connected to rough endoplasmic reticulum (ER) membranes. These results shed light on how membranes may be supplied and reorganized for autophagosomal biogenesis.
- London Research Institute United Kingdom
- University Medical Center Utrecht Netherlands
- Cancer Research UK United Kingdom
Intracellular Membranes/metabolism, Phagosomes, Phagosomes/ultrastructure, Endoplasmic Reticulum/ultrastructure, Animals, Intracellular Membranes, Endoplasmic Reticulum, Lipid Metabolism, Developmental Biology
Intracellular Membranes/metabolism, Phagosomes, Phagosomes/ultrastructure, Endoplasmic Reticulum/ultrastructure, Animals, Intracellular Membranes, Endoplasmic Reticulum, Lipid Metabolism, Developmental Biology
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