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Developmental Cell
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Developmental Cell
Article . 2009
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Developmental Cell
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The Curious Case of Bivalent Marks

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2009 English Publisher:Elsevier BVJournal:Developmental Cell, volume 17, pages 301-303 (issn: 1534-5807, Copyright policy )
Authors: Herz, Hans-Martin; Nakanishi, Shima; Shilatifard, Ali;

doi: 10.1016/j.devcel.2009.08.014

pmid: 19758552

The Curious Case of Bivalent Marks

Abstract

Bivalently marked chromatin, containing both histone H3 lysine 4 (H3K4) and H3K27 trimethylation, is a hallmark of developmentally regulated paused promoters in mammalian embryonic stem cells. In this issue of Developmental Cell, Akkers et al. report that Xenopus tropicalis embryos transition through early development without the requirement for bivalently marked promoters.

Related Organizations
Keywords

Models, Genetic, Transcription, Genetic, Lysine, Xenopus, Models, Biological, Chromatin, Nucleosomes, Protein Structure, Tertiary, Histones, Animals, Humans, Promoter Regions, Genetic, Embryonic Stem Cells, Developmental Biology

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 22
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
22
Average
Top 10%
Top 10%
hybrid