
pmid: 18694552
A new paper from Campellone et al. in a recent issue of Cell identifies WHAMM, a multifunctional protein that stimulates Arp2/3-mediated actin polymerization, binds and organizes microtubules, and influences the structure and efficiency of the Golgi complex. WHAMM's membrane localization at the entry face of the Golgi complex is novel for an actin nucleation-promoting factor, and highlights the importance of the cytoskeleton in organizing the secretory pathway.
Animals, Golgi Apparatus, Proteins, Microtubules, Actin-Related Protein 2-3 Complex, Actins, Developmental Biology
Animals, Golgi Apparatus, Proteins, Microtubules, Actin-Related Protein 2-3 Complex, Actins, Developmental Biology
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