
Wntless is a sorting receptor required for Wnt secretion. Wntless is retrieved from endosomes to the Golgi by retromer, permitting Wntless reutilization in Wnt transport. In the absence of retromer, Wntless is degraded in lysosomes and Wnt secretion is impaired.
Wnt Proteins, Vesicular Transport Proteins, Animals, Golgi Apparatus, Endosomes, Transport Vesicles, Models, Biological, Developmental Biology, Signal Transduction, trans-Golgi Network
Wnt Proteins, Vesicular Transport Proteins, Animals, Golgi Apparatus, Endosomes, Transport Vesicles, Models, Biological, Developmental Biology, Signal Transduction, trans-Golgi Network
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