Necrosis and the Serpin Under't

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2007 English Publisher:Elsevier BVJournal:Developmental Cell, volume 13, pages 464-465 (issn: 1534-5807,

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Authors: Abraham, Mary C.; Shaham, Shai;

doi: 10.1016/j.devcel.2007.09.008

pmid: 17925223

Necrosis and the Serpin Under't

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Abstract

Caspase proteases play essential roles in apoptotic cell death, while other proteases are active in necrotic cell death. In a recent paper in Cell, Luke et al. (2007) present findings demonstrating that a gene believed to be a natural protease inhibitor may have a role in preventing necrosis.

Related Organizations

Rockefeller University
United States

Keywords

Necrosis, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Lysosomes, Serpins, Developmental Biology

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