
pmid: 17681128
The fibroblast growth factors (FGFs) are key regulators of cell growth and differentiation during embryogenesis. They deliver both short-range and distant signals assisted by their proteoglycan (PG) coreceptors in the pericellular matrix. The study by Hou et al. (2007) has identified a novel autoinductive loop involving FGF and the secreted serine protease xHtrA1 that leads to the mobilization of latent FGF/PG complexes. These complexes are long-range messages for mesoderm induction and establishment of the embryonic body plan.
Extracellular Matrix Proteins, Embryo, Nonmammalian, Xenopus Proteins, Extracellular Matrix, Fibroblast Growth Factors, Xenopus laevis, Glypicans, Biglycan, Animals, Proteoglycans, Syndecan-4, Developmental Biology
Extracellular Matrix Proteins, Embryo, Nonmammalian, Xenopus Proteins, Extracellular Matrix, Fibroblast Growth Factors, Xenopus laevis, Glypicans, Biglycan, Animals, Proteoglycans, Syndecan-4, Developmental Biology
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 6 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
