Breaking Symmetry on Time
Copyright policy )Breaking Symmetry on Time
The habenular nuclei are a conserved relay center of telencephalic function, and they display bilateral asymmetry in many vertebrates. How this asymmetry is constructed in response to local lateralized cues remains poorly understood. A paper by Aizawa et al. (2007) in this issue of Developmental Cell highlights an unsuspected role for neuronal differentiation timing in the generation of structurally distinct left and right habenular nuclei.
Neurons, Habenula, Embryo, Nonmammalian, Time Factors, Receptors, Notch, Models, Neurological, Gene Expression Regulation, Developmental, Receptor Protein-Tyrosine Kinases, Cell Differentiation, Nerve Tissue Proteins, Zebrafish Proteins, Animals, RNA, Messenger, Cation Transport Proteins, Zebrafish, Developmental Biology, Body Patterning, Signal Transduction
Neurons, Habenula, Embryo, Nonmammalian, Time Factors, Receptors, Notch, Models, Neurological, Gene Expression Regulation, Developmental, Receptor Protein-Tyrosine Kinases, Cell Differentiation, Nerve Tissue Proteins, Zebrafish Proteins, Animals, RNA, Messenger, Cation Transport Proteins, Zebrafish, Developmental Biology, Body Patterning, Signal Transduction
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