
pmid: 16890154
Canonical Wnt signaling, below the Fz/LRP receptor complex, induces the stabilization of beta-catenin via an unresolved mechanism. A recent study in Genes & Development introduces a new player and deepens our understanding of this signaling relay that plays pivotal roles during embryogenesis and tumorigenesis.
Wnt Proteins, Microfilament Proteins, Animals, Humans, Models, Biological, Frizzled Receptors, LDL-Receptor Related Proteins, beta Catenin, Developmental Biology, Signal Transduction
Wnt Proteins, Microfilament Proteins, Animals, Humans, Models, Biological, Frizzled Receptors, LDL-Receptor Related Proteins, beta Catenin, Developmental Biology, Signal Transduction
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