Mechanisms of Mechanotransduction
Copyright policy )Mechanisms of Mechanotransduction
Essentially all organisms from bacteria to humans are mechanosensitive. Physical forces regulate a large array of physiological processes, and dysregulation of mechanical responses contributes to major human diseases. A survey of both specialized and widely expressed mechanosensitive systems suggests that physical forces provide a general means of altering protein conformation to generate signals. Specialized systems differ mainly in having acquired efficient mechanisms for transferring forces to the mechanotransducers.
Myocardium, Cell Cycle, Adaptation, Physiological, Mechanotransduction, Cellular, Models, Biological, Muscle, Smooth, Vascular, Protein Structure, Tertiary, Neoplasms, Physical Stimulation, Hypertension, Animals, Humans, Stress, Mechanical, Lung, Developmental Biology, Signal Transduction
Myocardium, Cell Cycle, Adaptation, Physiological, Mechanotransduction, Cellular, Models, Biological, Muscle, Smooth, Vascular, Protein Structure, Tertiary, Neoplasms, Physical Stimulation, Hypertension, Animals, Humans, Stress, Mechanical, Lung, Developmental Biology, Signal Transduction
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