ER Retention of Signaling Modules
Copyright policy )ER Retention of Signaling Modules
A novel strategy for controlling developmental signaling pathways, which uses specific ER retention mechanisms, has emerged from several recent studies. A paper by Yamamoto et al. (2005) identifies a new protein termed Shisa that inhibits both Wnt- and FGF-signaling pathways during Xenopus gastrulation by mediating ER retention of the Wnt receptor Frizzled and the FGF receptor.
Xenopus, Proteins, Xenopus Proteins, Endoplasmic Reticulum, Receptors, Fibroblast Growth Factor, Frizzled Receptors, Wnt Proteins, Animals, Intercellular Signaling Peptides and Proteins, Developmental Biology, Signal Transduction
Xenopus, Proteins, Xenopus Proteins, Endoplasmic Reticulum, Receptors, Fibroblast Growth Factor, Frizzled Receptors, Wnt Proteins, Animals, Intercellular Signaling Peptides and Proteins, Developmental Biology, Signal Transduction
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