To B or Not to B: PIP2 Answers the Question
Copyright policy )To B or Not to B: PIP2 Answers the Question
In a recent issue of Molecular Cell, Papayannopoulos et al. (2005) show that N-WASP activation of actin-related protein2/3 (Arp2/3) is ultrasensitive to PI(4,5)P(2) concentration. We discuss how interactions between basic regions in proteins and negatively charged membranes can produce sharp on-off switches that may regulate biological activity.
- King’s University United States
- Howard Hughes Medical Institute United States
- Cornell University United States
Models, Molecular, Phosphatidylinositol 4,5-Diphosphate, Binding Sites, Static Electricity, Wiskott-Aldrich Syndrome Protein, Neuronal, Nerve Tissue Proteins, Protein Structure, Tertiary, Cytoskeletal Proteins, Kinetics, Actin-Related Protein 3, Actin-Related Protein 2, Developmental Biology
Models, Molecular, Phosphatidylinositol 4,5-Diphosphate, Binding Sites, Static Electricity, Wiskott-Aldrich Syndrome Protein, Neuronal, Nerve Tissue Proteins, Protein Structure, Tertiary, Cytoskeletal Proteins, Kinetics, Actin-Related Protein 3, Actin-Related Protein 2, Developmental Biology
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).8 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!