Chk1 Activation and the Nuclear/Cytoplasmic Ratio
Copyright policy )Chk1 Activation and the Nuclear/Cytoplasmic Ratio
ATR and Chk1 are important components of a cell cycle checkpoint pathway. In this issue of Developmental Cell, Conn et al. shed a novel light on the molecular mechanism of Chk1 activation and raise the possibility of a developmental checkpoint that regulates Chk1 in response to the nuclear/cytoplasmic ratio.
- University of Chicago United States
- THE UNIVERSITY OF CHICAGO United States
Cell Nucleus, Cytoplasm, Cell Cycle, Gene Expression Regulation, Developmental, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Models, Biological, Enzyme Activation, Checkpoint Kinase 1, Animals, cdc25 Phosphatases, Protein Kinases, Developmental Biology
Cell Nucleus, Cytoplasm, Cell Cycle, Gene Expression Regulation, Developmental, Cell Cycle Proteins, Protein Serine-Threonine Kinases, Models, Biological, Enzyme Activation, Checkpoint Kinase 1, Animals, cdc25 Phosphatases, Protein Kinases, Developmental Biology
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