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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Drug Discovery Today...arrow_drop_down
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Drug Discovery Today Technologies
Article . 2004 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Drug Discovery Today Technologies
Article . 2005 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
Drug Discovery Today Technologies
Article . 2014
Data sources: Europe PubMed Central
Drug Discovery Today Technologies
Article . 2014
Data sources: Europe PubMed Central
https://dx.doi.org/10.1016/j.d...
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Physiology-based pharmacokinetic modeling: ready to be used

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2004 English Publisher:Elsevier BVJournal:Drug Discovery Today: Technologies, volume 1, pages 449-456 (issn: 1740-6749, Copyright policy )
Authors: Walter, Schmitt; Stefan, Willmann;

doi: 10.1016/j.ddtec.2004.09.006 , 10.1016/j.ddtec.2005.01.001

pmid: 24981626 , 24981765

Physiology-based pharmacokinetic modeling: ready to be used

Abstract

Physiology-based pharmacokinetic (PBPK) modeling is well recognized as a technology for mechanistically simulating and predicting the fate of substances in a mammalian body. Today, the demand for this methodology is higher than ever. The pharma industry and regulatory agencies are looking for new methods, which help to speed up and increase the efficiency of the development process for new drugs. Implementing PBPK modeling in the drug research and development workflow contributes significantly to reach this goal.:

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
46
Top 10%
Top 10%
Top 10%
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