Model organisms and target discovery

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2004 English Publisher:Elsevier BVJournal:Drug Discovery Today: Technologies, volume 1, pages 55-59 (issn: 1740-6749,

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Authors: Marco, Muda; Sean, McKenna;

doi: 10.1016/j.ddtec.2004.08.001

pmid: 24981268

Model organisms and target discovery

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Abstract

The wealth of information harvested from full genomic sequencing projects has not generated a parallel increase in the number of novel targets for therapeutic intervention. Several pharmaceutical companies have realized that novel drug targets can be identified and validated using simple model organisms. After decades of service in basic research laboratories, yeasts, worms, flies, fishes, and mice are now the cornerstones of modern drug discovery programs.:

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