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Cell Polarity: Getting the PARty Started

Getting the PARty Started
descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2019 Netherlands English Publisher:Elsevier BVJournal:Current Biology, volume 29, pages R637-R639 (issn: 0960-9822, Copyright policy )
Authors: Boxem, Mike; van den Heuvel, Sander;

doi: 10.1016/j.cub.2019.05.032

pmid: 31287983

Cell Polarity: Getting the PARty Started

Abstract

Polarity establishment is a key developmental process, but what determines its timing is poorly understood. New research in Caenorhabditis elegans demonstrates that the PAR polarity system extensively reconfigures before becoming competent to polarize. By inhibiting membrane localization of anterior PAR proteins, AIR-1 (aurora A) and PLK-1 (polo kinase) prevent premature polarization.

Country
Netherlands
Related Organizations
Keywords

Polo-Like Kinase 1, Taverne, Animals, Cell Polarity, Cues, Protein Serine-Threonine Kinases, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Aurora Kinase A

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 26
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
26
Top 10%
Average
Top 10%
Green
hybrid