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Aneuploidy: Tolerating Tolerance

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2015Publisher:Elsevier BVJournal:Current Biology, volume 25, pages R771-R773 (issn: 0960-9822,

Authors: Aimée M. Dudley; Gareth A. Cromie;

doi: 10.1016/j.cub.2015.06.056

pmid: 26325142

Aneuploidy: Tolerating Tolerance

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Abstract

Individuals, and cells, vary in their ability to tolerate aneuploidy, an unbalanced chromosome complement. Tolerance mechanisms can be karyotype-specific or general. General tolerance mechanisms may allow cells to benefit from the phenotypic plasticity conferred by access to multiple aneuploid states.

Related Organizations

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Keywords

Agricultural and Biological Sciences(all), Models, Genetic, Biochemistry, Genetics and Molecular Biology(all), Dosage Compensation, Genetic, Genes, Fungal, Gene Dosage, Saccharomyces cerevisiae, Aneuploidy

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	11
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%

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3. Good health

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