Stem Cell Niches: Famished Paneth Cells, Gluttonous Stem Cells
Copyright policy )Stem Cell Niches: Famished Paneth Cells, Gluttonous Stem Cells
Adult tissue stem cells adjust to environmental changes. A new study in the mouse intestine reveals that caloric restriction causes Paneth cells to repress mTORC1 signaling; this in turn stimulates proliferation of neighboring stem cells.
- Brigham and Women's Faulkner Hospital United States
- Harvard University United States
- Dana-Farber Cancer Institute United States
Paneth Cells, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Stem Cells, TOR Serine-Threonine Kinases, Proteins, Mechanistic Target of Rapamycin Complex 1, Intestines, Mice, Multiprotein Complexes, Animals, Stem Cell Niche, Caloric Restriction
Paneth Cells, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Stem Cells, TOR Serine-Threonine Kinases, Proteins, Mechanistic Target of Rapamycin Complex 1, Intestines, Mice, Multiprotein Complexes, Animals, Stem Cell Niche, Caloric Restriction
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