Cytosine Methylation: Remaining Faithful
Copyright policy )Cytosine Methylation: Remaining Faithful
DNA methyltransferase-1 (DNMT1) has a higher specific activity on hemimethylated DNA than on unmethylated DNA, but this preference is too small to explain the faithful mitotic inheritance of genomic methylation patterns. New genetic studies in plants and mammals have identified a novel factor that increases the fidelity of maintenance methylation.
- King’s University United States
- Harvard University United States
- Columbia University United States
- Department of Organismic and Evolutionary Biology Harvard University United States
DNA (Cytosine-5-)-Methyltransferase 1, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Ubiquitin-Protein Ligases, Nuclear Proteins, DNA, DNA Methylation, Cytosine, Mice, CCAAT-Enhancer-Binding Proteins, Animals, DNA (Cytosine-5-)-Methyltransferases, Genome, Plant
DNA (Cytosine-5-)-Methyltransferase 1, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Ubiquitin-Protein Ligases, Nuclear Proteins, DNA, DNA Methylation, Cytosine, Mice, CCAAT-Enhancer-Binding Proteins, Animals, DNA (Cytosine-5-)-Methyltransferases, Genome, Plant
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