Genetic Imprinting: Conflict at the Callipyge Locus
Copyright policy )Genetic Imprinting: Conflict at the Callipyge Locus
The imprinted Dlk1-Gtl2 region of the mammalian genome - which in sheep encompasses the Callipyge locus, known for its unusual mode of inheritance - encodes a number of maternally expressed miRNAs. Five of these miRNAs, hosted by the antisense transcript antiPeg11, have now been shown to target degradation of the paternally expressed Peg11 mRNA by an RNAi-mediated mechanism.
- Babraham Institute United Kingdom
Mammals, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Inheritance Patterns, Proteins, Genomic Imprinting, MicroRNAs, Gene Components, Mutation, Animals, Humans, RNA Interference, RNA, Long Noncoding, RNA, Messenger, Glycoproteins
Mammals, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Inheritance Patterns, Proteins, Genomic Imprinting, MicroRNAs, Gene Components, Mutation, Animals, Humans, RNA Interference, RNA, Long Noncoding, RNA, Messenger, Glycoproteins
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