Plant RNAi: How aViral Silencing Suppressor Inactivates siRNA

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2004 English Publisher:Elsevier BVJournal:Current Biology, volume 14, pages R198-R200 (issn: 0960-9822,

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Authors: Zamore, Phillip D.;

doi: 10.1016/j.cub.2004.02.021

pmid: 15028237

Plant RNAi: How aViral Silencing Suppressor Inactivates siRNA

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Abstract

The three-dimensional structure of an siRNA bound to the tombusvirus p19 protein--a suppressor of gene silencing--provides a first glimpse into how plant viruses can defeat their host's anti-viral RNAi defenses.

Related Organizations

University of Massachusetts Medical School
United States

Keywords

Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Protein Conformation, Plants, Tombusvirus, MicroRNAs, Viral Proteins, Nucleic Acid Conformation, RNA Interference, RNA, Small Interfering

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