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Long non-coding RNAs in hematopoietic regulation

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Dec 2018 English Publisher:Springer Science and Business Media LLCJournal:Cell Regeneration, volume 7, pages 27-32 (issn: 2045-9769, Copyright policy )
Authors: Yanmin Si; Jia Yu; Fang Wang; Yue Ren; Weiqian Li;

doi: 10.1016/j.cr.2018.08.001

pmid: 30671227

pmc: PMC6326246

Long non-coding RNAs in hematopoietic regulation

Abstract

Long non-coding RNAs (lncRNAs) have crucial roles via tethering with DNA, RNA or protein in diverse biological processes. These lncRNA-mediated interactions enhance gene regulatory networks and modulate a wide range of downstream genes. It has been demonstrated that several lncRNAs act as key regulators in hematopoiesis. This review highlights the roles of lncRNAs in normal hematopoietic development and discusses how lncRNA dysregulation correlates with disease prognoses and phenotypes.

Related Organizations
Keywords

Medicine (General), R5-920, QH301-705.5, Biology (General), Article

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 22
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
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    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
22
Top 10%
Average
Top 10%
Green
gold