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Therapy Monitoring with Fluorine-18 FDG-PET and Fluorine-18 FDG-PET/CT

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2008Publisher:Elsevier BVJournal:PET Clinics, volume 3, pages 217-226 (issn: 1556-8598,

Authors: Ken Herrmann; Hinrich Wieder;

doi: 10.1016/j.cpet.2008.08.009

pmid: 27156465

Therapy Monitoring with Fluorine-18 FDG-PET and Fluorine-18 FDG-PET/CT

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Abstract

PET with the glucose analog [18F]-FDG is increasingly used to monitor tumor response in patients undergoing chemotherapy and chemoradiotherapy. The clinical value of FDG PET for differentiation of residual tumor and therapy-induced fibrosis has been documented for gastrointestinal cancer. Furthermore, quantitative assessment of therapy-induced changes in tumor [18F]-FDG uptake may allow the prediction of tumor response and patient outcome very early in the course of therapy. This suggests that FDG PET may be used to identify nonresponders early during neoadjuvant chemoradiotherapy, allowing for early modifications of the treatment protocol.

Related Organizations

Technical University of Munich
Germany
Rechts der Isar Hospital
Germany

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