Name: [18F]Fluorodeoxyglucose PET in Large Vessel Vasculitis
Creator: Martin A. Walter
Keywords: Fluorodeoxyglucose F18, Positron-Emission Tomography, Giant Cell Arteritis, Humans, Radiopharmaceuticals, Tomography, X-Ray Computed, Sensitivity and Specificity, Takayasu Arteritis, 3. Good health

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2006 English Publisher:Elsevier BVJournal:PET Clinics, volume 1, pages 179-189 (issn: 1556-8598,

Authors: Martin A. Walter;

doi: 10.1016/j.cpet.2006.02.001 , 10.1016/j.rcl.2007.05.012

pmid: 27157083 , 17706537

[18F]Fluorodeoxyglucose PET in Large Vessel Vasculitis

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Abstract

[(18)F]fluorodeoxyglucose (FDG) PET is a noninvasive metabolic imaging modality based on the regional distribution of [(18)F]FDG that is highly effective in assessing the activity and extent of giant cell arteritis and Takayasu's arteritis, respectively. Metabolic imaging using [(18)F]FDG-PET has been shown to identify more affected vascular regions than morphologic imaging with MRI in both diseases. The visual grading of vascular [(18)F]FDG uptake helps to discriminate arteritis from atherosclerosis and therefore provides high specificity. High sensitivity is attained by scanning during the active inflammatory phase. Thus, [(18)F]FDG-PET has the potential to develop into a valuable tool in the diagnostic workup of giant cell arteritis and Takayasu's arteritis.

Related Organizations

University Hospital of Basel
Switzerland

Keywords

Fluorodeoxyglucose F18, Positron-Emission Tomography, Giant Cell Arteritis, Humans, Radiopharmaceuticals, Tomography, X-Ray Computed, Sensitivity and Specificity, Takayasu Arteritis

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