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A disruption of colour priming following continuous theta burst transcranial magnetic stimulation

Authors: Banissy, Michael J.; Walsh, Vincent; Muggleton, Neil G.;

A disruption of colour priming following continuous theta burst transcranial magnetic stimulation

Abstract

It is well established that the presentation of one visual attribute (e.g., colour, motion) can improve the likelihood of the same attribute being detected on a subsequent trial (Tulving and Schacter, 1990). There is growing evidence to suggest that this effect is driven in a bottom-upmanner (Maljkovic and Nakayama, 1994), which is dependent upon functionally specialized extrastriate regions (Walsh et al., 2000; Campana et al., 2002; Kristjansson et al., 2005, 2007). For example, lesions to macaque area V4 and TEO abolish colour and form priming (Walsh et al., 2000). Also, in humans, transcranial magnetic stimulation (TMS) targetedatV5/MThasbeen shown to abolish motion priming (Campana et al., 2002). However, there is also evidence that relativelyminormanipulationof the stimuli can alter the level atwhich priming seems to occur (see Kristjansson and Campana, 2010). For example, lower visual levels can mediate motion priming when a prime of the same type as the probe stimulus is used, whereas priming occurs at a higher level when the prime and probe differ in type (Campana et al., 2008). Here, we sought to establish the effects of continuous theta burst TMS (cTBS; Huang et al., 2005) targeted at human left V4 (Morita et al., 2004), left V5/MT or the vertex, on the perceptual priming of colour. Based on the assumption that colour priming is a consequence of neural activity in colour selective extrastriate regions, we expected that cTBS targeted at human V4would disrupt colour priming, but that thiswould not occur following cTBS to our active control sites (V5/MT and the vertex). Eighteenparticipants (six per stimulation group) completed a colour priming paradigm (Fig. 1a) prior to (baseline) and following cTBS targeted at human V4, V5/MT or the vertex. During the task, participants were presented with a coloured

Country
United Kingdom
Keywords

Neurology, Task Performance and Analysis, Clinical Neurology, Motor Cortex, Visual Perception, Color, Humans, Theta Rhythm, Transcranial Magnetic Stimulation

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    3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
Green
hybrid