Post-transcriptional gene silencing in neurons

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2004 English Publisher:Elsevier BVJournal:Current Opinion in Neurobiology, volume 14, pages 654-659 (issn: 0959-4388,

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Authors: Henry C, Zeringue; Martha, Constantine-Paton;

doi: 10.1016/j.conb.2004.08.009

pmid: 15464901

Post-transcriptional gene silencing in neurons

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Abstract

The techniques evolving from the rapidly developing field of small RNAs promise accessible approaches to dissecting cellular and molecular mechanisms of higher brain function. Here, a current overview of the technology is presented, along with an outline of how these approaches might help neuroscientists to more rapidly uncover the cellular and molecular bases of behavior.

Related Organizations

Massachusetts Institute of Technology
United States
McGovern Institute for Brain Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA
United States

Keywords

Neurons, Genetic Vectors, Brain, Nerve Tissue Proteins, Gene Targeting, Models, Animal, Animals, Humans, RNA Interference, RNA, Messenger, RNA, Small Interfering

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