Precious metal economy

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2006 English Publisher:Elsevier BVJournal:Cell Metabolism, volume 4, pages 99-101 (issn: 1550-4131,

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Authors: Merchant, Sabeeha S.; Sagasti, Alvaro;

doi: 10.1016/j.cmet.2006.07.003

pmid: 16890535

Precious metal economy

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Abstract

The zebrafish is emerging as a system of choice for modeling human disease. In this issue of Cell Metabolism, Mendelsohn et al. (2006) describe a model for Menkes disease, a genetic disorder in copper utilization. Using genetic and chemical screens, the authors highlight the impact of maternal nutrition on embryo development. The work reveals a hierarchy of temporal and dosage-dependent phenotypes for copper nutrition.

Related Organizations

University of California, Los Angeles
United States

Keywords

Disease Models, Animal, Physiology, Animals, Humans, Cell Biology, Menkes Kinky Hair Syndrome, Molecular Biology, Copper, Zebrafish

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