Small Lymphocytic Lymphoma Presenting As a Paraneoplastic Syndrome With Acute Central Nervous System Demyelination
Copyright policy )Small Lymphocytic Lymphoma Presenting As a Paraneoplastic Syndrome With Acute Central Nervous System Demyelination
Chronic lymphocytic leukemia (CLL)/small lymphocytic lym-phoma (SLL) is a mature B-cell neoplasm characterized by accu-mulation of functionally incompetent clonal lymphocytes with thesame morphologic and immunophenotypic features. CLL and SLLhave the same cellular basis but SLL lacks significant peripheralblood (PB) lymphocytosis. CLL is the most common leukemia inthe United States, accounting for 30% of all leukemias, and SLLaccounts for less than 5% of all non-Hodgkin lymphomas. Themedian age at diagnosis is 65 years, and there is a Caucasian malepredominance.
- Tufts Medical Center United States
Paraneoplastic Syndromes, Biopsy, Brain, Immunohistochemistry, Leukemia, Lymphocytic, Chronic, B-Cell, Magnetic Resonance Imaging, Diagnosis, Differential, Antibodies, Monoclonal, Murine-Derived, Treatment Outcome, Doxorubicin, Antineoplastic Combined Chemotherapy Protocols, Humans, Prednisone, Female, Lymph Nodes, Rituximab, Tomography, X-Ray Computed, Cyclophosphamide, Aged, Demyelinating Diseases
Paraneoplastic Syndromes, Biopsy, Brain, Immunohistochemistry, Leukemia, Lymphocytic, Chronic, B-Cell, Magnetic Resonance Imaging, Diagnosis, Differential, Antibodies, Monoclonal, Murine-Derived, Treatment Outcome, Doxorubicin, Antineoplastic Combined Chemotherapy Protocols, Humans, Prednisone, Female, Lymph Nodes, Rituximab, Tomography, X-Ray Computed, Cyclophosphamide, Aged, Demyelinating Diseases
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