In developing countries, sexually transmitted infections (STIs) account for 10% to 20% of adult patients attending government health facilities. A young population, with 36% younger than 15 years, unbalanced male/female ratio(1000:933), increasing urbanization, illiteracy, poverty, sexual promiscuity, and lack of health education account for a high prevalence of STIs. Epidemiologic surveillance system and laboratory diagnostic facilities, especially point-of-care diagnosis, are inadequate in India. Antibiotic resistance in causative pathogens is an important hurdle in their control. Currently, syndromic management is the most common approach in India.