Regimens for Cirrhotic Patients
Copyright policy )Regimens for Cirrhotic Patients
Therapy for hepatitis C has entered the era of all-oral direct-acting antiviral agents. Sustained response rates are now greater than 90% for all genotypes, although patients with cirrhosis remain the most difficult to treat. There are limited data for patients with cirrhosis and with hepatitis C genotypes 4 and 6 with cirrhosis. Genotype 3 patients with cirrhosis need additional strategies to achieve the sustained virologic response rates seen in genotype 1 patients with cirrhosis. This article outlines the currently available therapies for patients with cirrhosis and hepatitis C across all genotypes, with suggested management strategies.
- Indiana University United States
- Indiana University School of Medicine United States
- Indiana University Health United States
Liver Cirrhosis, Genotype, Hepacivirus, Hepatitis C, Chronic, Viral Nonstructural Proteins, RNA-Dependent RNA Polymerase, Antiviral Agents, Retreatment, Humans, RNA, Viral, Drug Therapy, Combination, Protease Inhibitors, Treatment Failure, Nucleic Acid Synthesis Inhibitors
Liver Cirrhosis, Genotype, Hepacivirus, Hepatitis C, Chronic, Viral Nonstructural Proteins, RNA-Dependent RNA Polymerase, Antiviral Agents, Retreatment, Humans, RNA, Viral, Drug Therapy, Combination, Protease Inhibitors, Treatment Failure, Nucleic Acid Synthesis Inhibitors
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