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YopM Puts Caspase-1 on Ice

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2012 English Publisher:Elsevier BVJournal:Cell Host & Microbe, volume 12, pages 737-738 (issn: 1931-3128, Copyright policy )
Authors: Edward A. Miao; Ine Jorgensen;

doi: 10.1016/j.chom.2012.11.006

pmid: 23245318

pmc: PMC3590850

YopM Puts Caspase-1 on Ice

Abstract

Caspase-1-mediated detection of pathogens is a potent arm of the innate immune system. LaRock and Cookson (2012) show that the Yersinia type III secretion effector, YopM, directly inhibits caspase-1.

Related Organizations
Keywords

Cancer Research, Inflammasomes, Virulence Factors, Yersinia pestis, Caspase 1, Ice, Yersinia, Immunology and Microbiology(all), Animals, Molecular Biology, Bacterial Outer Membrane Proteins

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
hybrid
Related to Research communities
Cancer Research