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To Translocate or Not: That Is the Problem

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2011 English Publisher:Elsevier BVJournal:Cell Host & Microbe, volume 10, pages 179-180 (issn: 1931-3128, Copyright policy )
Authors: Wayne I. Lencer; Rodney K. Tweten;

doi: 10.1016/j.chom.2011.08.009

pmid: 21925105

pmc: PMC3178040

To Translocate or Not: That Is the Problem

Abstract

The botulinum toxins (BoNTs) enter the cytosol of host cells by translocation across the limiting membrane of acidic endosomes. In this issue, Sun et al. (2011) show that BoNT binding to one of its cell surface receptors renders it susceptible to pH-dependent conformational changes required for translocation and cellular toxicity.

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Keywords

Cancer Research, Immunology and Microbiology(all), Molecular Biology

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
hybrid
Related to Research communities
Cancer Research