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Regulation of Protein Secretion by … Protein Secretion?

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 2008 English Publisher:Elsevier BVJournal:Cell Host & Microbe, volume 4, pages 190-191 (issn: 1931-3128,

Authors: Sarah M. Fortune; Krishnamohan Atmakuri;

doi: 10.1016/j.chom.2008.08.009

pmid: 18779042

Regulation of Protein Secretion by … Protein Secretion?

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Abstract

Mycobacterium tuberculosis (Mtb) requires an alternative protein secretion system, ESX1, for virulence. Recently, Raghavan et al. (2008) reported a new regulatory circuit that may explain how ESX1 activity is controlled during infection. Mtb appears to regulate ESX1 by modulating transcription of associated genes rather than structural components of the secretion system itself.

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Keywords

Cancer Research, Virulence Factors, Gene Expression Regulation, Bacterial, Mycobacterium tuberculosis, Protein Transport, Bacterial Proteins, Immunology and Microbiology(all), Humans, Tuberculosis, Molecular Biology

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