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Cell Systems
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Reconciling Epigenetic Memory and Transcriptional Responsiveness

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 2017 United Kingdom English Publisher:Elsevier BVJournal:Cell Systems, volume 4, pages 373-374 (issn: 2405-4712, Copyright policy )Funded by:EC | REPLENICHE
Authors: Fisher, AG; Stumpf, MPH; Merkenschlager, M;

doi: 10.1016/j.cels.2017.04.005

pmid: 28448796

handle: 10044/1/48672

Reconciling Epigenetic Memory and Transcriptional Responsiveness

Abstract

The molecular basis of cellular memory is important but poorly understood. Using estimates of histone dynamics, Martin Howard and colleagues construct a mathematical model that helps to explain both the stability and flexibility of Polycomb-mediated gene regulation in cellular memory.

Country
United Kingdom
Related Organizations
Keywords

Biochemistry & Molecular Biology, 570, Science & Technology, Polycomb-Group Proteins, Cell Biology, PROPAGATION, Chromatin, Histones, Gene Expression Regulation, Drosophila Proteins, Life Sciences & Biomedicine

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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Average
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