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Cell Reports
Article . 2022 . Peer-reviewed
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Cell Reports
Article . 2022
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UPF1 adds an m6A feather to its (de)cap

Authors: Michelle R, Gibbs; Guillaume F, Chanfreau;

UPF1 adds an m6A feather to its (de)cap

Abstract

The N6-methyladenosine modification (m6A) modulates eukaryotic mRNA decay. In this issue of Cell Reports, Boo et al. describe a mechanism for degradation of m6A-containing mRNAs by 5'-decapping, which occurs through the recruitment of the degradation factor UPF1 via the m6A reader protein YTHDF2.

Related Organizations
Keywords

Adenosine, RNA Stability, Animals, RNA-Binding Proteins, RNA, Messenger, Feathers

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Top 10%
Average
Top 10%
gold